Panama City (PTY) to Sao Paulo (SAO): 3,160 miles (5,086 km) great-circle, about 6h 50m nonstop by our estimate. Cheapest fare observed: $630 round-trip on Avianca, with 1 stop, departing May 13, 2026.
$630 round-trip, Avianca AV59, departing 2026-05-13 at 10:10, returning 2026-05-15. The recorded itinerary left on a Wednesday, returning on a Friday 2 nights later; the fare was observed 18 days before departure. "Book this flight" opens Kiwi.com with the same airline and dates.
At $630, it ranked 16th of the 30 round-trip fares we recorded from PTY (median $593). That is 19.9 cents per great-circle mile (round-trip price over one-way distance), below the PTY median of 31.9 cents across 30 round-trip routes.
Routes from PTY of similar length: Boston (2,356 mi) at $634 and Antofagasta (2,326 mi) at $661.
Avianca had the cheapest fare on 8 of 30 PTY routes. It is the 9th longest of the 30 routes we track from PTY.
Of 20 departure airports with a fare to Sao Paulo, Panama City (PTY) ranked 8th at $630. Lowest: $59 from Rio de Janeiro (GIG); highest: $1830 from Brisbane (BNE); 4 nonstop. Cheapest-fare airlines (routes): Copa (4), Arajet (3), Avianca (2), TAAG Angola Airlines (2), Azul (1) and Cathay Pacific (1), plus 7 more.
Travelpayouts fares (cheapest per route, observed April 25, 2026); OurAirports coordinates and elevations; IANA zones America/Panama, America/Sao_Paulo; flight time is our estimate.