San Francisco (SFO) to Cairo (CAI): 7,460 miles (12,005 km) great-circle, about 15h 25m nonstop by our estimate. Cheapest fare observed: $685 round-trip on ITA Airways, with 1 stop, departing April 29, 2026.
$685 round-trip, ITA Airways AZ641, departing 2026-04-29 at 15:15, returning 2026-05-06. The recorded itinerary left on a Wednesday, returning on a Wednesday 7 nights later; the fare was observed 4 days before departure. "Book this flight" opens Kiwi.com with the same airline and dates.
At $685, it ranked 16th of the 30 round-trip fares we recorded from SFO (median $646). That is 9.2 cents per great-circle mile (round-trip price over one-way distance), below the SFO median of 16.9 cents across 30 round-trip routes.
Routes from SFO of similar length: Kabul (7,394 mi) at $1237 and Delhi (7,694 mi) at $876.
SFO to CAI is the only one of 30 SFO routes where ITA Airways priced cheapest. It is the 4th longest of the 30 routes we track from SFO.
Of 30 departure airports with a fare to Cairo, San Francisco (SFO) ranked 17th at $685. Lowest: $157 from Riyadh (RUH); highest: $1516 from Washington DC (DCA); 3 nonstop. Cheapest-fare airlines (routes): ITA Airways (3), Pegasus Airlines (3), Qatar (3), Air Canada (2), easyJet (2) and flynas (2), plus 15 more.
Travelpayouts fares (cheapest per route, observed April 25, 2026); OurAirports coordinates and elevations; IANA zones America/Los_Angeles, Africa/Cairo; flight time is our estimate.