Panama City (PTY) to Boston (BOS): 2,356 miles (3,791 km) great-circle, about 5h 15m nonstop by our estimate. Cheapest fare observed: $634 round-trip on Avianca, with 1 stop, departing May 22, 2026.
$634 round-trip, Avianca AV316, departing 2026-05-22 at 05:30, returning 2026-05-27. The recorded itinerary left on a Friday, returning on a Wednesday 5 nights later; the fare was observed 27 days before departure. "Book this flight" opens Kiwi.com with the same airline and dates.
At $634, it ranked 17th of the 30 round-trip fares we recorded from PTY (median $593). That is 26.9 cents per great-circle mile (round-trip price over one-way distance), below the PTY median of 31.9 cents across 30 round-trip routes.
Routes from PTY of similar length: Antofagasta (2,326 mi) at $661 and New York (2,208 mi) at $517.
Avianca had the cheapest fare on 8 of 30 PTY routes. It is the 10th longest of the 30 routes we track from PTY.
Of 22 departure airports with a fare to Boston, Panama City (PTY) ranked 19th at $634. Lowest: $101 from Fort Lauderdale (FLL); highest: $1271 from Nairobi (NBO); 5 nonstop. Cheapest-fare airlines (routes): American Airlines (6), Frontier (5), Spirit (4), Southwest (3), Avianca (1) and Brussels Airlines (1), plus 2 more.
That depends on your passport and trip, so check the official source for United States: U.S. Customs and Border Protection: international visitors. Connecting elsewhere? Check that country's transit rules too.
Travelpayouts fares (cheapest per route, observed April 25, 2026); OurAirports coordinates and elevations; IANA zones America/Panama, America/New_York; flight time is our estimate.