Panama City (PTY) to Madrid (MAD): 5,068 miles (8,157 km) great-circle, about 10h 40m nonstop by our estimate. Cheapest fare observed: $828 round-trip on Turkish, with 1 stop, departing May 18, 2026.
$828 round-trip, Turkish TK904, departing 2026-05-18 at 22:20, returning 2026-06-13. The recorded itinerary left on a Monday, returning on a Saturday 26 nights later; the fare was observed 23 days before departure. "Book this flight" opens Kiwi.com with the same airline and dates.
At $828, it ranked 23rd of the 30 round-trip fares we recorded from PTY (median $593). That is 16.3 cents per great-circle mile (round-trip price over one-way distance), below the PTY median of 31.9 cents across 30 round-trip routes.
Routes from PTY of similar length: Barcelona (5,364 mi) at $1004 and Milan (5,681 mi) at $1036.
Turkish had the cheapest fare on 3 of 30 PTY routes. It is the 8th longest of the 30 routes we track from PTY.
Of 35 departure airports with a fare to Madrid, Panama City (PTY) ranked 22nd at $828. Lowest: $46 from Lisbon (LIS); highest: $1698 from Sydney (SYD); 13 nonstop. Cheapest-fare airlines (routes): United Airlines (4), Wizz Air (4), Air China (2), American Airlines (2), Ryanair (2) and TAP Portugal (2), plus 17 more.
That depends on your passport and trip, so check the official source for Spain: European Commission: Schengen visa policy. Connecting elsewhere? Check that country's transit rules too.
Travelpayouts fares (cheapest per route, observed April 25, 2026); OurAirports coordinates and elevations; IANA zones America/Panama, Europe/Madrid; flight time is our estimate.